• Rat NME1 (Non Metastatic Cells 1, Protein NM23A Expressed In) Sandwich ELISA Kit (STJE0010990)

Rat NME1 (Non Metastatic Cells 1, Protein NM23A Expressed In) Sandwich ELISA Kit (STJE0010990)

SKU:
STJE0010990

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.108ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This NME1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Nme1
Gene ID: 191575
Uniprot ID: NDKA_RAT
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair.
Protein Name Nucleoside Diphosphate Kinase A
Ndk A
Ndp Kinase A
Metastasis Inhibition Factor Nm23
Tumor Metastatic Process-Associated Protein
Database Links Reactome: R-RNO-499943
Reactome: -RNO-9748787
Reactome: -RNO-9755088
Cellular Localisation Cytoplasm
Nucleus
Alternative ELISA Names Nucleoside Diphosphate Kinase A ELISA kit
Ndk A ELISA kit
Ndp Kinase A ELISA kit
Metastasis Inhibition Factor Nm23 ELISA kit
Tumor Metastatic Process-Associated Protein ELISA kit
Nme1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance