| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
25pg/mL |
| Detection Limit: |
78.1-5000pg/mL |
| Short Description: |
This L1CAM Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
L1cam |
| Gene ID: |
50687 |
| Uniprot ID: |
L1CAM_RAT |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Isoform 2 is predominantly found in the brain, while isoform 1 is found in the peripheral nervous system. |
| Post Translational Modifications | |
| Function | Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity. |
| Protein Name | Neural Cell Adhesion Molecule L1N-Cam-L1Ncam-L1Nerve-Growth Factor-Inducible Large External GlycoproteinNileCd Antigen Cd171 |
| Database Links | Reactome: R-RNO-373760Reactome: -RNO-437239Reactome: -RNO-445095Reactome: -RNO-445144 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionGrowth ConeColocalized With Shtn1 In Close Apposition With Actin Filaments In Filopodia And Lamellipodia Of Axonal Growth Cones Of Hippocampal Neurons |
| Alternative ELISA Names | Neural Cell Adhesion Molecule L1 ELISA kitN-Cam-L1 ELISA kitNcam-L1 ELISA kitNerve-Growth Factor-Inducible Large External Glycoprotein ELISA kitNile ELISA kitCd Antigen Cd171 ELISA kitL1cam ELISA kitCaml1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
