• Rat GRIN1 (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 1) Sandwich ELISA Kit (STJE0009301)

Rat GRIN1 (Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate 1) Sandwich ELISA Kit (STJE0009301)

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STJE0009301

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.062ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This GRIN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Grin1
Gene ID: 24408
Uniprot ID: NMDZ1_RAT
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected throughout the brain, in brain cortex, cerebellum, thalamus and olfactory bulb.
Post Translational Modifications NMDA is probably regulated by C-terminal phosphorylation of an isoform of NR1 by PKC. Dephosphorylated on Ser-897 probably by protein phosphatase 2A (PPP2CB). Its phosphorylated state is influenced by the formation of the NMDAR-PPP2CB complex and the NMDAR channel activity.
Function Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
Protein Name Glutamate Receptor Ionotropic - Nmda 1
Glun1
Glutamate Nmda Receptor Subunit Zeta-1
N-Methyl-D-Aspartate Receptor Subunit Nr1
Nmd-R1
Database Links Reactome: R-RNO-3928662
Reactome: -RNO-438066
Reactome: -RNO-5673001
Reactome: -RNO-8849932
Reactome: -RNO-9609736
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Postsynaptic Cell Membrane
Postsynaptic Density
Enriched In Postsynaptic Plasma Membrane And Postsynaptic Densities
Alternative ELISA Names Glutamate Receptor Ionotropic - Nmda 1 ELISA kit
Glun1 ELISA kit
Glutamate Nmda Receptor Subunit Zeta-1 ELISA kit
N-Methyl-D-Aspartate Receptor Subunit Nr1 ELISA kit
Nmd-R1 ELISA kit
Grin1 ELISA kit
Nmdar1 ELISA kit
output

Information sourced from Uniprot.org

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