| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
5.9pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This GPI Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Gpi |
| Gene ID: |
292804 |
| Uniprot ID: |
G6PI_RAT |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway. ISGylated. |
| Function | In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
| Protein Name | Glucose-6-Phosphate IsomeraseGpiAutocrine Motility FactorAmfNeuroleukinNlkPhosphoglucose IsomerasePgiPhosphohexose IsomerasePhi |
| Database Links | Reactome: R-RNO-5628897Reactome: -RNO-6798695Reactome: -RNO-70171Reactome: -RNO-70263 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative ELISA Names | Glucose-6-Phosphate Isomerase ELISA kitGpi ELISA kitAutocrine Motility Factor ELISA kitAmf ELISA kitNeuroleukin ELISA kitNlk ELISA kitPhosphoglucose Isomerase ELISA kitPgi ELISA kitPhosphohexose Isomerase ELISA kitPhi ELISA kitGpi ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
