Applications: |
ELISA |
Reactivity: |
Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.071ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This FATP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
3 hrs |
Gene Symbol: |
Slc27a1Uniprot ID=S27A1_RAT" |
Immunogen Region: |
Ready-To-Use |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed in muscle. |
Post Translational Modifications | |
Function | Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane. Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Probably involved in fatty acid transport across the blood barrier. |
Protein Name | Long-Chain Fatty Acid Transport Protein 1Arachidonate--Coa LigaseFatty Acid Transport ProteinFatty Acid Transport Protein 1Fatp-1Long-Chain-Fatty-Acid--Coa LigaseSolute Carrier Family 27 Member 1Very Long-Chain Acyl-Coa Synthetase |
Database Links | |
Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinEndomembrane SystemCytoplasmPlasma Membrane And Intracellular MembranesAt Least In AdipocytesIn AdipocytesBut Not MyocytesInsulin Via The Mtorc1 Signaling Pathway Induces A Rapid Translocation Of Slc27a1 From Intracellular Compartments To The Plasma MembraneParalleled By Increased Lcfa UptakeInsulin-Dependent Translocation From The Cytoplasm To The Cell Membrane Is Regulated By Eprs1Predominantly Cytoplasmic In Myocytes |
Alternative ELISA Names | Long-Chain Fatty Acid Transport Protein 1 ELISA kitArachidonate--Coa Ligase ELISA kitFatty Acid Transport Protein ELISA kitFatty Acid Transport Protein 1 ELISA kitFatp-1 ELISA kitLong-Chain-Fatty-Acid--Coa Ligase ELISA kitSolute Carrier Family 27 Member 1 ELISA kitVery Long-Chain Acyl-Coa Synthetase ELISA kitSlc27a1 ELISA kitFatp ELISA kitFatp1 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance