| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
5.5pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This EMMPRIN Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Bsg |
| Gene ID: |
25246 |
| Uniprot ID: |
BASI_RAT |
| Sample Type: |
serum, plasma, lung lavage fluid or other biological fluids. |
| Tissue Specificity | Isoform 2: Expressed in the skeletal muscle, liver, small intestine, kidney, testis, brain, heart and spleen. Also present in various immature cells and endothelia. |
| Post Translational Modifications | |
| Function | Isoform 1: Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. Isoform 2: Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells. Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1 and SLC16A3 to the plasma membrane. Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling. Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells. Plays an important role in spermatogenesis.mediates interactions between germ cells and Sertoli cell and is essential for the development/differentiation of germ cells to round spermatids. |
| Protein Name | BasiginGlycoprotein Ce9Ox-47 AntigenCd Antigen Cd147 |
| Database Links | |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinPhotoreceptor Inner SegmentCell ProjectionCiliumPhotoreceptor Outer SegmentIsoform 2: Cell MembraneEndoplasmic Reticulum MembraneBasolateral Cell Membrane |
| Alternative ELISA Names | Basigin ELISA kitGlycoprotein Ce9 ELISA kitOx-47 Antigen ELISA kitCd Antigen Cd147 ELISA kitBsg ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
