• Rat EMMPRIN (Extracellular Matrix Metalloproteinase Inducer) Sandwich ELISA Kit Ready-To-Use (STJE0015016)

Rat EMMPRIN (Extracellular Matrix Metalloproteinase Inducer) Sandwich ELISA Kit Ready-To-Use (STJE0015016)

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STJE0015016

£492.50 - £676.50
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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 5.5pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This EMMPRIN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Bsg
Gene ID: 25246
Uniprot ID: BASI_RAT
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, lung lavage fluid or other biological fluids.
Tissue Specificity Isoform 2: Expressed in the skeletal muscle, liver, small intestine, kidney, testis, brain, heart and spleen. Also present in various immature cells and endothelia.
Post Translational Modifications
Function Isoform 1: Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. Isoform 2: Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells. Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1 and SLC16A3 to the plasma membrane. Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling. Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells. Plays an important role in spermatogenesis.mediates interactions between germ cells and Sertoli cell and is essential for the development/differentiation of germ cells to round spermatids.
Protein Name Basigin
Glycoprotein Ce9
Ox-47 Antigen
Cd Antigen Cd147
Database Links
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Photoreceptor Inner Segment
Cell Projection
Cilium
Photoreceptor Outer Segment
Isoform 2: Cell Membrane
Endoplasmic Reticulum Membrane
Basolateral Cell Membrane
Alternative ELISA Names Basigin ELISA kit
Glycoprotein Ce9 ELISA kit
Ox-47 Antigen ELISA kit
Cd Antigen Cd147 ELISA kit
Bsg ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance