• Rat CRHR2 (Corticotropin Releasing Hormone Receptor 2) Sandwich ELISA Kit Ready-To-Use (STJE0014521)

Rat CRHR2 (Corticotropin Releasing Hormone Receptor 2) Sandwich ELISA Kit Ready-To-Use (STJE0014521)

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STJE0014521

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.134ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This CRHR2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Crhr2
Gene ID: 64680
Uniprot ID: CRFR2_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Predominantly expressed in limbic regions of the brain such as the lateral septum, the entorhinal cortex, the hypothalamic ventromedial nucleus and several amygdaloid nuclei. Also detectable in lung, kidney and heart.
Post Translational Modifications A N-glycosylation site within the signal peptide impedes its proper cleavage and function.
Function G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Protein Name Corticotropin-Releasing Factor Receptor 2
Crf-R-2
Crf-R2
Crfr-2
Corticotropin-Releasing Hormone Receptor 2
Crh-R-2
Crh-R2
Database Links Reactome: R-RNO-373080
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Corticotropin-Releasing Factor Receptor 2 ELISA kit
Crf-R-2 ELISA kit
Crf-R2 ELISA kit
Crfr-2 ELISA kit
Corticotropin-Releasing Hormone Receptor 2 ELISA kit
Crh-R-2 ELISA kit
Crh-R2 ELISA kit
Crhr2 ELISA kit
Crf2r ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance