Tissue Specificity | The shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine. |
Post Translational Modifications | The precursor is cleaved by proteases to produce a number of active cholecystokinins. Sulfation of Tyr-97 is essential for receptor activation. |
Function | This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. |
Protein Name | CholecystokininCck Cleaved Into - Cholecystokinin-39Cck39 - Cholecystokinin-33Cck33 - Cholecystokinin-22Cck22 - Cholecystokinin-12Cck12 - Cholecystokinin-8Cck8 |
Database Links | Reactome: R-RNO-375276Reactome: -RNO-416476 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Cholecystokinin ELISA kitCck Cleaved Into - Cholecystokinin-39 ELISA kitCck39 - Cholecystokinin-33 ELISA kitCck33 - Cholecystokinin-22 ELISA kitCck22 - Cholecystokinin-12 ELISA kitCck12 - Cholecystokinin-8 ELISA kitCck8 ELISA kitCck ELISA kit |
output | |
Information sourced from Uniprot.org