• Rat ATP1b1 (ATPase, Na+/K+ Transporting Beta 1 Polypeptide) Sandwich ELISA Kit Ready-To-Use (STJE0013753)

Rat ATP1b1 (ATPase, Na+/K+ Transporting Beta 1 Polypeptide) Sandwich ELISA Kit Ready-To-Use (STJE0013753)

SKU:
STJE0013753

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.057ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ATP1b1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Atp1b1
Gene ID: 25650
Uniprot ID: AT1B1_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in the brain, liver, testes and anterior prostate (at protein level).
Post Translational Modifications Glutathionylated. N-glycosylated.
Function This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Plays a role in innate immunity by enhancing virus-triggered induction of interferons (IFNs) and interferon stimulated genes (ISGs). Mechanistically, enhances the ubiquitination of TRAF3 and TRAF6 as well as the phosphorylation of TAK1 and TBK1. Involved in cell adhesion and establishing epithelial cell polarity.
Protein Name Sodium/Potassium-Transporting Atpase Subunit Beta-1
Sodium/Potassium-Dependent Atpase Subunit Beta-1
Database Links Reactome: R-RNO-5578775
Reactome: -RNO-936837
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Apical Cell Membrane
Sarcolemma
Colocalizes With Obscn At The Intercalated Disk And Sarcolemma In Cardiomyocytes
Localizes In Long Striations At The Level Of Z And M Lines
Alternative ELISA Names Sodium/Potassium-Transporting Atpase Subunit Beta-1 ELISA kit
Sodium/Potassium-Dependent Atpase Subunit Beta-1 ELISA kit
Atp1b1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance