• Rat ACPP (Acid Phosphatase, Prostatic) Sandwich ELISA Kit (STJE0006860)

Rat ACPP (Acid Phosphatase, Prostatic) Sandwich ELISA Kit (STJE0006860)

SKU:
STJE0006860

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.069ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ACPP Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Acp3
Gene ID: 56780
Uniprot ID: PPAP_RAT
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed in prostate epithelium. Also expressed in the pelvic nerve and sacral spinal cord. Localizes in peptidergic and non-peptidergic nociceptive (pain-sensing) neurons.
Post Translational Modifications N-glycosylated.
Function Isoform 1: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: In addition to its tyrosine phosphatase activity, also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP. This extracellular adenosine leads to a decrease in chronic pain by activating A1R in nociceptive neurons.
Protein Name Prostatic Acid Phosphatase
5'-Nucleotidase
5'-Nt
Acid Phosphatase 3
Ecto-5'-Nucleotidase
Fluoride-Resistant Acid Phosphatase
Frap
Protein Tyrosine Phosphatase Acp3
Thiamine Monophosphatase
Tmpase
Database Links Reactome: R-RNO-6798695
Cellular Localisation Isoform 1: Secreted
Isoform 2: Cell Membrane
Single-Pass Type I Membrane Protein
Lysosome Membrane
Appears To Shuttle Between The Cell Membrane And Intracellular Vesicles
Colocalizes With Flot1 At Cell Membrane And In Intracellular Vesicles
Colocalizes With Lamp2 On The Lysosome Membrane
Alternative ELISA Names Prostatic Acid Phosphatase ELISA kit
5'-Nucleotidase ELISA kit
5'-Nt ELISA kit
Acid Phosphatase 3 ELISA kit
Ecto-5'-Nucleotidase ELISA kit
Fluoride-Resistant Acid Phosphatase ELISA kit
Frap ELISA kit
Protein Tyrosine Phosphatase Acp3 ELISA kit
Thiamine Monophosphatase ELISA kit
Tmpase ELISA kit
Acp3 ELISA kit
Acpp ELISA kit
output

Information sourced from Uniprot.org

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