| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
MSF Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Tissue Specificity | Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. |
| Peptide Name | Septin-9Mll Septin-Like Fusion Protein Msf-AMll Septin-Like Fusion ProteinOvarian/Breast SeptinOv/Br SeptinSeptin D1 |
| Cellular Localisation | CytoplasmCytoskeletonIn An Epithelial Cell LineConcentrates At Cell-Cell Contact AreasAfter Tgf-Beta1 Treatment And Induction Of Epithelial To Mesenchymal TransitionColocalizes Partly With Actin Stress FibersDuring Bacterial InfectionDisplays A Collar Shape Structure Next To Actin At The Pole Of Invading Bacteria |
| Alternative Peptide Names | Septin-9 proteinMll Septin-Like Fusion Protein Msf-A proteinMll Septin-Like Fusion Protein proteinOvarian/Breast Septin proteinOv/Br Septin proteinSeptin D1 proteinSEPTIN9 proteinKIAA0991 proteinMSF proteinSEPT9 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
