• Mouse TSPAN30 (Tetraspanin 30) Sandwich ELISA Kit Ready-To-Use (STJE0019235)

Mouse TSPAN30 (Tetraspanin 30) Sandwich ELISA Kit Ready-To-Use (STJE0019235)

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STJE0019235

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.064ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This TSPAN30 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Cd63
Gene ID: 12512
Uniprot ID: CD63_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: plasma, tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Ubiquitous. Strongly expressed in kidney. Detected in spleen, bone marrow, peripheral blood mononuclear cells and macrophages.
Post Translational Modifications Palmitoylated at a low, basal level in unstimulated platelets. The level of palmitoylation increases when platelets are activated by thrombin (in vitro).
Function Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
Protein Name Cd63 Antigen
Cd Antigen Cd63
Database Links Reactome: R-MMU-114608
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lysosome Membrane
Late Endosome Membrane
Endosome
Multivesicular Body
Melanosome
Secreted
Extracellular Exosome
Cell Surface
Also Found In Weibel-Palade Bodies Of Endothelial Cells
Located In Platelet Dense Granules
Detected In A Subset Of Pre-Melanosomes
Detected On Intralumenal Vesicles (Ilvs) Within Multivesicular Bodies
Alternative ELISA Names Cd63 Antigen ELISA kit
Cd Antigen Cd63 ELISA kit
Cd63 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance