• Mouse TMPRSS2 (Transmembrane Protease, Serine 2) Sandwich ELISA Kit (STJE0012657)

Mouse TMPRSS2 (Transmembrane Protease, Serine 2) Sandwich ELISA Kit (STJE0012657)

SKU:
STJE0012657

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.113ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This TMPRSS2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Tmprss2
Gene ID: 50528
Uniprot ID: TMPS2_MOUSE
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Larynx, trachea and bronchi, lung, prostate and kidney.
Post Translational Modifications Proteolytically processed.by an autocatalytic mechanism.
Function Plasma membrane-anchored serine protease that cleaves at arginine residues. Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia. (Microbial infection) Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9) and is involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.
Protein Name Transmembrane Protease Serine 2
Epitheliasin
Plasmic Transmembrane Protein X Cleaved Into - Transmembrane Protease Serine 2 Non-Catalytic Chain - Transmembrane Protease Serine 2 Catalytic Chain
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Transmembrane Protease Serine 2 Catalytic Chain: Secreted
Activated By Cleavage And Secreted
Alternative ELISA Names Transmembrane Protease Serine 2 ELISA kit
Epitheliasin ELISA kit
Plasmic Transmembrane Protein X Cleaved Into - Transmembrane Protease Serine 2 Non-Catalytic Chain - Transmembrane Protease Serine 2 Catalytic Chain ELISA kit
Tmprss2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance