Host: |
HEK293 cells |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Mouse ROR1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Endotoxin: |
Less than 1EU per Mu g by the LAL method. |
Gene Symbol: |
Ror1 |
Gene ID: |
26563 |
Uniprot ID: |
ROR1_MOUSE |
Immunogen Region: |
Gln30-Tyr406 |
Immunogen: |
Recombinant Mouse ROR1 Protein is expressed from Expi293 with His tag at the C-terminal.;It contains Gln30-Tyr406. |
Function | Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. |
Protein Name | Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1Mror1Neurotrophic Tyrosine Kinase - Receptor-Related 1 |
Database Links | Reactome: R-MMU-5140745 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxon |
Alternative Protein Names | Inactive Tyrosine-Protein Kinase Transmembrane Receptor Ror1 proteinMror1 proteinNeurotrophic Tyrosine Kinase - Receptor-Related 1 proteinRor1 proteinNtrkr1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance