| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.055ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This PEBP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Pebp1 |
| Gene ID: |
23980 |
| Uniprot ID: |
PEBP1_MOUSE |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | HCNP is expressed in brain. Increased expression in aged senescence-accelerated mice. |
| Post Translational Modifications | |
| Function | Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor. |
| Protein Name | Phosphatidylethanolamine-Binding Protein 1Pebp-1Hcnppp Cleaved Into - Hippocampal Cholinergic Neurostimulating PeptideHcnp |
| Database Links | Reactome: R-MMU-5674135Reactome: -MMU-5675221 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Phosphatidylethanolamine-Binding Protein 1 ELISA kitPebp-1 ELISA kitHcnppp Cleaved Into - Hippocampal Cholinergic Neurostimulating Peptide ELISA kitHcnp ELISA kitPebp1 ELISA kitPbp ELISA kitPebp ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
