| Host: |
Pichia |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse PDGF-AA-N-His protein was developed from pichia and has a target region of N-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of 30 % CAN, 0.1 % TFA. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Pdgfa |
| Gene ID: |
18590 |
| Uniprot ID: |
PDGFA_MOUSE |
| Immunogen Region: |
Ser87-Arg196 |
| Immunogen: |
Recombinant Mouse PDGF-AA Protein is produced by Pichia expression system. The target protein is expressed with sequence (Ser87-Arg196) of Mouse PDGF-AA (Accession #NP_032834.1) fused with a 6×His tag at the N-terminus. |
| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB. |
| Protein Name | Platelet-Derived Growth Factor Subunit APdgf Subunit APdgf-1Platelet-Derived Growth Factor A ChainPlatelet-Derived Growth Factor Alpha Polypeptide |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-1257604Reactome: -MMU-186763Reactome: -MMU-186797Reactome: -MMU-5673001Reactome: -MMU-6811558 |
| Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
| Alternative Protein Names | Platelet-Derived Growth Factor Subunit A proteinPdgf Subunit A proteinPdgf-1 proteinPlatelet-Derived Growth Factor A Chain proteinPlatelet-Derived Growth Factor Alpha Polypeptide proteinPdgfa protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
