| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
18.75pg/mL |
| Detection Limit: |
31.2-2000pg/mL |
| Short Description: |
This PDE3B Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Pde3b |
| Gene ID: |
18576 |
| Uniprot ID: |
PDE3B_MOUSE |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | Abundant in adipose tissues. |
| Post Translational Modifications | Phosphorylation at Ser-273 mediates insulin-induced activation of PDE3B. |
| Function | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Regulates angiogenesis by inhibiting the cAMP-dependent guanine nucleotide exchange factor RAPGEF3 and downstream phosphatidylinositol 3-kinase gamma-mediated signaling. Controls cardiac contractility by reducing cAMP concentration in cardiocytes. |
| Protein Name | Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3bCgipde1Cyclic Gmp-Inhibited Phosphodiesterase BCgi-Pde B |
| Database Links | Reactome: R-MMU-165160Reactome: -MMU-418555 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Cgmp-Inhibited 3' -5'-Cyclic Phosphodiesterase 3b ELISA kitCgipde1 ELISA kitCyclic Gmp-Inhibited Phosphodiesterase B ELISA kitCgi-Pde B ELISA kitPde3b ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
