• Mouse NEP (Neprilysin) Sandwich ELISA Kit Ready-To-Use (STJE0017304)

Mouse NEP (Neprilysin) Sandwich ELISA Kit Ready-To-Use (STJE0017304)

SKU:
STJE0017304

£472.50 - £647.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 33pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This NEP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Mme
Gene ID: 17380
Uniprot ID: NEP_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity
Post Translational Modifications Myristoylation is a determinant of membrane targeting. Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity.
Function Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of the atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Protein Name Neprilysin
Atriopeptidase
Enkephalinase
Neutral Endopeptidase 24.11
Nep
Neutral Endopeptidase
Skin Fibroblast Elastase
Sfe
Cd Antigen Cd10
Database Links Reactome: R-MMU-2022377
Reactome: -MMU-5578768
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative ELISA Names Neprilysin ELISA kit
Atriopeptidase ELISA kit
Enkephalinase ELISA kit
Neutral Endopeptidase 24.11 ELISA kit
Nep ELISA kit
Neutral Endopeptidase ELISA kit
Skin Fibroblast Elastase ELISA kit
Sfe ELISA kit
Cd Antigen Cd10 ELISA kit
Mme ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance