| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
35pg/mL |
| Detection Limit: |
78.1-5000pg/mL |
| Short Description: |
This MSTN Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Mstn |
| Gene ID: |
17700 |
| Uniprot ID: |
GDF8_MOUSE |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
| Tissue Specificity | Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. |
| Post Translational Modifications | Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase. |
| Function | Acts specifically as a negative regulator of skeletal muscle growth. |
| Protein Name | Growth/Differentiation Factor 8Gdf-8Myostatin |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Growth/Differentiation Factor 8 ELISA kitGdf-8 ELISA kitMyostatin ELISA kitMstn ELISA kitGdf8 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
