| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.108ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This LPCAT2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Lpcat2 |
| Gene ID: |
270084 |
| Uniprot ID: |
PCAT2_MOUSE |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Highest expression is found in resident macrophages and casein-induced neutrophils followed by skin, colon, spleen and thioglycollate-induced macrophages. Detected in erythroleukemic cells but not in reticulocytes. |
| Post Translational Modifications | |
| Function | Exhibits both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Involved in the regulation of lipid droplet number and size. |
| Protein Name | Lysophosphatidylcholine Acyltransferase 2Lpc Acyltransferase 2Lpcat-2Lysopc Acyltransferase 21-Acylglycerol-3-Phosphate O-Acyltransferase 111-Agp Acyltransferase 111-Agpat 111-Acylglycerophosphocholine O-Acyltransferase1-Alkenylglycerophosphocholine O-Acyltransferase1-Alkylglycerophosphocholine O-AcetyltransferaseAcetyl-Coa -Lyso-Platelet-Activating Factor AcetyltransferaseAcetyl-Coa -Lyso-Paf AcetyltransferaseLyso-Paf AcetyltransferaseLysopafatAcyltransferase-Like 1 |
| Database Links | Reactome: R-MMU-1482788 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Ii Membrane ProteinGolgi Apparatus MembraneCell MembraneLipid Droplet |
| Alternative ELISA Names | Lysophosphatidylcholine Acyltransferase 2 ELISA kitLpc Acyltransferase 2 ELISA kitLpcat-2 ELISA kitLysopc Acyltransferase 2 ELISA kit1-Acylglycerol-3-Phosphate O-Acyltransferase 11 ELISA kit1-Agp Acyltransferase 11 ELISA kit1-Agpat 11 ELISA kit1-Acylglycerophosphocholine O-Acyltransferase ELISA kit1-Alkenylglycerophosphocholine O-Acyltransferase ELISA kit1-Alkylglycerophosphocholine O-Acetyltransferase ELISA kitAcetyl-Coa -Lyso-Platelet-Activating Factor Acetyltransferase ELISA kitAcetyl-Coa -Lyso-Paf Acetyltransferase ELISA kitLyso-Paf Acetyltransferase ELISA kitLysopafat ELISA kitAcyltransferase-Like 1 ELISA kitLpcat2 ELISA kitAytl1 ELISA kitAytl1a ELISA kitLpcat2a ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
