| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.136ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This IQGAP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Iqgap1 |
| Gene ID: |
29875 |
| Uniprot ID: |
IQGA1_MOUSE |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in the kidney (at protein level). |
| Post Translational Modifications | |
| Function | Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest. |
| Protein Name | Ras Gtpase-Activating-Like Protein Iqgap1 |
| Database Links | Reactome: R-MMU-373753Reactome: -MMU-5626467Reactome: -MMU-5674135Reactome: -MMU-6798695Reactome: -MMU-8980692Reactome: -MMU-9013106Reactome: -MMU-9013149Reactome: -MMU-9013404Reactome: -MMU-9013406Reactome: -MMU-9013420Reactome: -MMU-9013424 |
| Cellular Localisation | Cell MembraneNucleusCytoplasmApical Cell MembraneBasolateral Cell MembraneSubcellular Distribution Is Regulated By The Cell CycleNuclear Levels Increase At G1/S Phase |
| Alternative ELISA Names | Ras Gtpase-Activating-Like Protein Iqgap1 ELISA kitIqgap1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
