• Mouse GDH (Glutamate Dehydrogenase 1) Sandwich ELISA Kit Ready-To-Use (STJE0015506)

Mouse GDH (Glutamate Dehydrogenase 1) Sandwich ELISA Kit Ready-To-Use (STJE0015506)

SKU:
STJE0015506

£453.50 - £619.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.07U/L
Detection Limit: 0.156-10U/L
Short Description: This GDH Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Glud1
Gene ID: 14661
Uniprot ID: DHE3_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Acetylation of Lys-84 is observed in liver mitochondria from fasted mice but not from fed mice. ADP-ribosylated by SIRT4, leading to inactivate glutamate dehydrogenase activity. Stoichiometry shows that ADP-ribosylation occurs in one subunit per catalytically active homohexamer.
Function Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. Plays a role in insulin homeostasis. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate.
Protein Name Glutamate Dehydrogenase 1 - Mitochondrial
Gdh 1
Database Links Reactome: R-MMU-2151201
Reactome: -MMU-8964539
Cellular Localisation Mitochondrion
Endoplasmic Reticulum
Mostly Translocates Into The Mitochondria
Only A Small Amount Of The Protein Localizes To The Endoplasmic Reticulum
Alternative ELISA Names Glutamate Dehydrogenase 1 - Mitochondrial ELISA kit
Gdh 1 ELISA kit
Glud1 ELISA kit
Glud ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance