Applications: |
ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.49ng/mL |
Detection Limit: |
1.56-100ng/mL |
Short Description: |
This GAS6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
Gas6 |
Gene ID: |
14456 |
Uniprot ID: |
GAS6_MOUSE |
Sample Type: |
serum, plasma or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. |
Function | Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. |
Protein Name | Growth Arrest-Specific Protein 6Gas-6Axl Receptor Tyrosine Kinase Ligand |
Database Links | Reactome: R-MMU-114608Reactome: -MMU-159763Reactome: -MMU-159782Reactome: -MMU-202733Reactome: -MMU-381426Reactome: -MMU-8957275 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Growth Arrest-Specific Protein 6 ELISA kitGas-6 ELISA kitAxl Receptor Tyrosine Kinase Ligand ELISA kitGas6 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance