| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
13.6pg/mL |
| Detection Limit: |
31.2-2000pg/mL |
| Short Description: |
This FGF13 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Fgf13 |
| Gene ID: |
14168 |
| Uniprot ID: |
FGF13_MOUSE |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Detected in brain, eye and heart. In brain, the different isoforms display different patterns of expression. Expressed in brain and heart (at protein level). Isoform 3 is highly expressed in cardiac myocytes while isoform 1 is the most abundant in brain. |
| Post Translational Modifications | May be phosphorylated. |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons. Isoform 1: Seems not to be involved in neuroblast polarization and migration but regulates axon branching. |
| Protein Name | Fibroblast Growth Factor 13Fgf-13Fibroblast Growth Factor Homologous Factor 2Fhf-2 |
| Database Links | |
| Cellular Localisation | Cell ProjectionFilopodiumGrowth ConeDendriteCell MembraneSarcolemmaCytoplasmNot SecretedLocalizes To The Lateral Membrane And Intercalated Disks Of MyocytesIsoform 1: NucleusIsoform 2: CytoplasmNucleusIsoform 3: Cytoplasm |
| Alternative ELISA Names | Fibroblast Growth Factor 13 ELISA kitFgf-13 ELISA kitFibroblast Growth Factor Homologous Factor 2 ELISA kitFhf-2 ELISA kitFgf13 ELISA kitFhf2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
