| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.069ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This FceRI Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Fcer1a |
| Gene ID: |
14125 |
| Uniprot ID: |
FCERA_MOUSE |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Expressed in bone marrow mast cells, as well as in the pineal gland at night. |
| Post Translational Modifications | |
| Function | High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions. |
| Protein Name | High Affinity Immunoglobulin Epsilon Receptor Subunit AlphaFc-Epsilon Ri-AlphaFceriIge Fc Receptor Subunit Alpha |
| Database Links | Reactome: R-MMU-2454202Reactome: -MMU-2730905Reactome: -MMU-2871796Reactome: -MMU-2871809Reactome: -MMU-2871837 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha ELISA kitFc-Epsilon Ri-Alpha ELISA kitFceri ELISA kitIge Fc Receptor Subunit Alpha ELISA kitFcer1a ELISA kitFce1a ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
