• Mouse FBXL3 (F-Box And Leucine Rich Repeat Protein 3) Sandwich ELISA Kit (STJE0008820)

Mouse FBXL3 (F-Box And Leucine Rich Repeat Protein 3) Sandwich ELISA Kit (STJE0008820)

SKU:
STJE0008820

£335.50 - £645.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.059ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This FBXL3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Fbxl3
Gene ID: 50789
Uniprot ID: FBXL3_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Ubiquitously expressed but enriched in brain. Diffusely expressed in the suprachiasmatic nucleus, SCN.
Post Translational Modifications Undergoes autophagy-mediated degradation in the liver in a time-dependent manner.
Function Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.
Protein Name F-Box/Lrr-Repeat Protein 3
F-Box And Leucine-Rich Repeat Protein 3a
F-Box/Lrr-Repeat Protein 3a
Protein After-Hours
Protein Overtime
Database Links Reactome: R-MMU-8951664
Reactome: -MMU-983168
Cellular Localisation Nucleus
Cytoplasm
Predominantly Nuclear
Alternative ELISA Names F-Box/Lrr-Repeat Protein 3 ELISA kit
F-Box And Leucine-Rich Repeat Protein 3a ELISA kit
F-Box/Lrr-Repeat Protein 3a ELISA kit
Protein After-Hours ELISA kit
Protein Overtime ELISA kit
Fbxl3 ELISA kit
Afh ELISA kit
Fbl3a ELISA kit
Fbxl3a ELISA kit
Ovtm ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance