| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.106ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This FATP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Slc27a1 |
| Gene ID: |
26457 |
| Uniprot ID: |
S27A1_MOUSE |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Higher expression in white adipose tissue than in heart. Highest expression in skeletal muscle, heart and fat. Lower levels in brain, kidney, lung, liver and testis. No expression in spleen or intestine. |
| Post Translational Modifications | |
| Function | Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (Probable). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Probably involved in fatty acid transport across the blood barrier. |
| Protein Name | Long-Chain Fatty Acid Transport Protein 1Arachidonate--Coa LigaseFatty Acid Transport ProteinFatty Acid Transport Protein 1Fatp-1Long-Chain-Fatty-Acid--Coa LigaseSolute Carrier Family 27 Member 1Vlc27a1Very Long-Chain Acyl-Coa Synthetase |
| Database Links | Reactome: R-MMU-804914 |
| Cellular Localisation | Cell MembraneSingle-Pass Membrane ProteinMitochondrion Outer MembraneEndomembrane SystemCytoplasmPlasma Membrane And Intracellular MembranesAt Least In AdipocytesIn AdipocytesBut Not MyocytesInsulin Via The Mtorc1 Signaling Pathway Induces A Rapid Translocation Of Slc27a1 From Intracellular Compartments To The Plasma MembraneParalleled By Increased Lcfa UptakeInsulin-Dependent Translocation From The Cytoplasm To The Cell Membrane Is Regulated By Eprs1Predominantly Cytoplasmic In Myocytes |
| Alternative ELISA Names | Long-Chain Fatty Acid Transport Protein 1 ELISA kitArachidonate--Coa Ligase ELISA kitFatty Acid Transport Protein ELISA kitFatty Acid Transport Protein 1 ELISA kitFatp-1 ELISA kitLong-Chain-Fatty-Acid--Coa Ligase ELISA kitSolute Carrier Family 27 Member 1 ELISA kitVlc27a1 ELISA kitVery Long-Chain Acyl-Coa Synthetase ELISA kitSlc27a1 ELISA kitFatp ELISA kitFatp1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
