• Mouse FATP1 (Fatty Acid Transport Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0015180)

Mouse FATP1 (Fatty Acid Transport Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0015180)

SKU:
STJE0015180

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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.106ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This FATP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Slc27a1
Gene ID: 26457
Uniprot ID: S27A1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Higher expression in white adipose tissue than in heart. Highest expression in skeletal muscle, heart and fat. Lower levels in brain, kidney, lung, liver and testis. No expression in spleen or intestine.
Post Translational Modifications
Function Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (Probable). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Probably involved in fatty acid transport across the blood barrier.
Protein Name Long-Chain Fatty Acid Transport Protein 1
Arachidonate--Coa Ligase
Fatty Acid Transport Protein
Fatty Acid Transport Protein 1
Fatp-1
Long-Chain-Fatty-Acid--Coa Ligase
Solute Carrier Family 27 Member 1
Vlc27a1
Very Long-Chain Acyl-Coa Synthetase
Database Links Reactome: R-MMU-804914
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Mitochondrion Outer Membrane
Endomembrane System
Cytoplasm
Plasma Membrane And Intracellular Membranes
At Least In Adipocytes
In Adipocytes
But Not Myocytes
Insulin Via The Mtorc1 Signaling Pathway Induces A Rapid Translocation Of Slc27a1 From Intracellular Compartments To The Plasma Membrane
Paralleled By Increased Lcfa Uptake
Insulin-Dependent Translocation From The Cytoplasm To The Cell Membrane Is Regulated By Eprs1
Predominantly Cytoplasmic In Myocytes
Alternative ELISA Names Long-Chain Fatty Acid Transport Protein 1 ELISA kit
Arachidonate--Coa Ligase ELISA kit
Fatty Acid Transport Protein ELISA kit
Fatty Acid Transport Protein 1 ELISA kit
Fatp-1 ELISA kit
Long-Chain-Fatty-Acid--Coa Ligase ELISA kit
Solute Carrier Family 27 Member 1 ELISA kit
Vlc27a1 ELISA kit
Very Long-Chain Acyl-Coa Synthetase ELISA kit
Slc27a1 ELISA kit
Fatp ELISA kit
Fatp1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance