| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse EPCR-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | Procr |
| Gene ID: | 19124 |
| Uniprot ID: | EPCR_MOUSE |
| Immunogen Region: | LEU18-SER214 |
| Immunogen: | Optimized DNA sequence encodingHMouse Endothelial protein C receptor-EPCR (LEU18-SER214 ) extracellular domain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed in endothelial cells. |
| Function | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex.plays a role in the protein C pathway controlling blood coagulation. |
| Protein Name | Endothelial Protein C ReceptorActivated Protein C ReceptorApc ReceptorCentrocyclinCentrosomal Protein Ccd41Endothelial Cell Protein C ReceptorCd Antigen Cd201 |
| Database Links | Reactome: R-MMU-140875Reactome: -MMU-202733 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Endothelial Protein C Receptor proteinActivated Protein C Receptor proteinApc Receptor proteinCentrocyclin proteinCentrosomal Protein Ccd41 proteinEndothelial Cell Protein C Receptor proteinCd Antigen Cd201 proteinProcr proteinEpcr protein |
Information sourced from Uniprot.org