• Mouse DDR1 (Discoidin Domain Receptor Family, Member 1) Sandwich ELISA Kit Ready-To-Use (STJE0014766)

Mouse DDR1 (Discoidin Domain Receptor Family, Member 1) Sandwich ELISA Kit Ready-To-Use (STJE0014766)

SKU:
STJE0014766

£453.50 - £619.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.047ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This DDR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Ddr1
Gene ID: 12305
Uniprot ID: DDR1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Detected in the cochlea and the organ of Corti in the inner ear. Isoform 1 is predominant and is expressed in developing embryo and adult brain. Isoform 2 is expressed in various epithelial cells.
Post Translational Modifications Autophosphorylated in response to fibrillar collagen binding.
Function Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.
Protein Name Epithelial Discoidin Domain-Containing Receptor 1
Epithelial Discoidin Domain Receptor 1
Cd167 Antigen-Like Family Member A
Cell Adhesion Kinase
Discoidin Receptor Tyrosine Kinase
Protein-Tyrosine Kinase Mpk-6
Tyrosine Kinase Ddr
Tyrosine-Protein Kinase Cak
Cd Antigen Cd167a
Database Links Reactome: R-MMU-3000171
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Epithelial Discoidin Domain-Containing Receptor 1 ELISA kit
Epithelial Discoidin Domain Receptor 1 ELISA kit
Cd167 Antigen-Like Family Member A ELISA kit
Cell Adhesion Kinase ELISA kit
Discoidin Receptor Tyrosine Kinase ELISA kit
Protein-Tyrosine Kinase Mpk-6 ELISA kit
Tyrosine Kinase Ddr ELISA kit
Tyrosine-Protein Kinase Cak ELISA kit
Cd Antigen Cd167a ELISA kit
Ddr1 ELISA kit
Cak ELISA kit
Eddr1 ELISA kit
Mpk6 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance