| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
6.3pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This DBN1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Dbn1 |
| Gene ID: |
56320 |
| Uniprot ID: |
DREB_MOUSE |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in the hippocampus, with expression in the pyramidal cells of CA1, CA2 and CA3 and in the granule cells of the dentate gyrus (at protein level). Highly expressed in brain, also present in stomach and to a lesser degree in kidney, colon, and urinary bladder. The E2 isoform is specifically expressed in adult stomach, kidney, and cultured cells. |
| Post Translational Modifications | |
| Function | Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections. Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS. Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines. Involved in memory-related synaptic plasticity in the hippocampus. |
| Protein Name | DrebrinDevelopmentally-Regulated Brain Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCell ProjectionDendriteCell CortexCell JunctionGrowth ConeIn The Absence Of AntigenEvenly Distributed Throughout Subcortical Regions Of The T-Cell Membrane And CytoplasmIn The Presence Of AntigenDistributes To The Immunological Synapse Forming At The T-Cell-Apc Contact AreaWhere It Localizes At The Peripheral And Distal Supramolecular Activation Clusters (Smac)Colocalized With Rufy3 And F-Actin At The Transitional Domain Of The Axonal Growth Cone |
| Alternative ELISA Names | Drebrin ELISA kitDevelopmentally-Regulated Brain Protein ELISA kitDbn1 ELISA kitDrba ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
