| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 14.5pg/mL |
| Detection Limit: | 31.2-2000pg/mL |
| Short Description: | This COL3a1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Col3a1 |
| Gene ID: | 12825 |
| Uniprot ID: | CO3A1_MOUSE |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in embryonic brain, specifically in the meninges, pial basement membrane and blood vessels (at protein level). |
| Post Translational Modifications | Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group. |
| Function | Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. |
| Protein Name | Collagen Alpha-1(Iii Chain |
| Database Links | Reactome: R-MMU-1442490Reactome: -MMU-1474244Reactome: -MMU-1650814Reactome: -MMU-186797Reactome: -MMU-198933Reactome: -MMU-2022090Reactome: -MMU-216083Reactome: -MMU-3000171Reactome: -MMU-3000178Reactome: -MMU-419037Reactome: -MMU-8874081Reactome: -MMU-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative ELISA Names | Collagen Alpha-1(Iii Chain ELISA kitCol3a1 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
