| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.106ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This COL12 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Col12a1 |
| Gene ID: |
12816 |
| Uniprot ID: |
COCA1_MOUSE |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
serum, plasma or other biological fluids. |
| Tissue Specificity | Highest expression in tendons, perichondrium, skin, cornea, sclera, blood vessels, and periosteum. |
| Post Translational Modifications | The triple-helical tail is stabilized by disulfide bonds at each end. Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates. O-glycosylation of isoform 2.glycosaminoglycan of chondroitin-sulfate type. |
| Function | Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. |
| Protein Name | Collagen Alpha-1(Xii Chain |
| Database Links | Reactome: R-MMU-1442490Reactome: -MMU-1650814Reactome: -MMU-2022090Reactome: -MMU-8948216 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative ELISA Names | Collagen Alpha-1(Xii Chain ELISA kitCol12a1 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
