Name: Mouse CD24 protein (Recombinant) (C-hFc) (STJP001430)
SKU: STJP001430
Availability: InStock

Mouse CD24 protein (Recombinant) (C-hFc) (STJP001430)

SKU:

STJP001430

£97.50 - £291.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	<0.1 EU/Mu g
Immunoreactivity:	Measured by its binding ability in a functional ELISA.Immobilized Human CD24 at 2 Mu g/mL (100 Mu L/well) can bind Human Siglec10 with a linear range of 40-900ng/mL.

Gene Symbol:	Cd24
Gene ID:	12484
Uniprot ID:	CD24_MOUSE
Immunogen:	Recombinant Mouse CD24 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn27-Gly53) of mouse CD24 (Accession #NP_033976.1) fused with a hFc tag at the C-terminus.
Immunogen Sequence:	NQTSVAPFPGNQNISASPNP SNATTRG

Post Translational Modifications	The identity of the N- and O-linked polysaccharides is not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc.
Function	May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Protein Name	Signal Transducer Cd24 Lymphocyte Antigen 52 Ly-52 M1/69-J11d Heat Stable Antigen Hsa Nectadrin R13-Ag X62 Heat Stable Antigen Cd Antigen Cd24
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor
Alternative Protein Names	Signal Transducer Cd24 protein Lymphocyte Antigen 52 protein Ly-52 protein M1/69-J11d Heat Stable Antigen protein Hsa protein Nectadrin protein R13-Ag protein X62 Heat Stable Antigen protein Cd Antigen Cd24 protein Cd24 protein Cd24a protein Ly-52 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP001243	Human CD24 protein (Active Recombinant) (C-hFc) (STJP001243)	HEK293 cells
STJP002828	Mouse BTLA protein (Recombinant) (C-hFC) (STJP002828)	HEK293 cells
STJP001508	Mouse CD8a protein (Recombinant) (C-hFc) (STJP001508)	HEK293 cells
STJP002875	Mouse IL1RL1 protein (Recombinant) (C-hFc) (STJP002875)	HEK293 cells
STJP002788	Mouse CD52 protein (Recombinant) (C-hFc) (STJP002788)	HEK293 cells

Mouse CD24 protein (Recombinant) (C-hFc) (STJP001430)