| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse CCL5-N-hFc protein was developed from hek293 cells and has a target region of N-hFc. For use in research applications. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Endotoxin: |
Less than 1EU per Mu g by the LAL method. |
| Gene Symbol: |
Ccl5 |
| Gene ID: |
20304 |
| Uniprot ID: |
CCL5_MOUSE |
| Immunogen Region: |
Ser24-Ser91 |
| Immunogen: |
Recombinant Mouse CCL5 Protein is expressed from Expi293 with hFc tag at the N-terminal.；It contains Ser24-Ser91. |
| Function | Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. |
| Protein Name | C-C Motif Chemokine 5MurantesSis-DeltaSmall-Inducible Cytokine A5T-Cell-Specific Protein Rantes |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 5 proteinMurantes proteinSis-Delta proteinSmall-Inducible Cytokine A5 proteinT-Cell-Specific Protein Rantes proteinCcl5 proteinScya5 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
