| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.106ng/mL |
| Detection Limit: |
0.312-20ng/mL |
| Short Description: |
This CACNa1F Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Cacna1fUniprot ID=CAC1F_MOUSE" |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Expressed in the inner and outer nuclear layers and the genglion cell layer of the retina. |
| Post Translational Modifications | |
| Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Activates at more negative voltages and does not undergo calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarization. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1fVoltage-Gated Calcium Channel Subunit Alpha Cav1.4 |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1f ELISA kitVoltage-Gated Calcium Channel Subunit Alpha Cav1.4 ELISA kitCacna1f ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
