| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.29ng/mL |
| Detection Limit: |
0.781-50ng/mL |
| Short Description: |
This AST2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Got2 |
| Gene ID: |
14719 |
| Uniprot ID: |
AATM_MOUSE |
| Sample Type: |
serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Detected in brain (at protein level). |
| Post Translational Modifications | Acetylation of Lys-296, Lys-345 and Lys-363 is observed in liver mitochondria from fasted mice but not from fed mice. |
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Protein Name | Aspartate Aminotransferase - MitochondrialMaspatFatty Acid-Binding ProteinFabp-1Glutamate Oxaloacetate Transaminase 2Kynurenine Aminotransferase 4Kynurenine Aminotransferase IvKynurenine--Oxoglutarate Transaminase 4Kynurenine--Oxoglutarate Transaminase IvPlasma Membrane-Associated Fatty Acid-Binding ProteinFabppmTransaminase A |
| Database Links | Reactome: R-MMU-389661Reactome: -MMU-70263Reactome: -MMU-8963693Reactome: -MMU-8964539 |
| Cellular Localisation | Mitochondrion MatrixCell Membrane |
| Alternative ELISA Names | Aspartate Aminotransferase - Mitochondrial ELISA kitMaspat ELISA kitFatty Acid-Binding Protein ELISA kitFabp-1 ELISA kitGlutamate Oxaloacetate Transaminase 2 ELISA kitKynurenine Aminotransferase 4 ELISA kitKynurenine Aminotransferase Iv ELISA kitKynurenine--Oxoglutarate Transaminase 4 ELISA kitKynurenine--Oxoglutarate Transaminase Iv ELISA kitPlasma Membrane-Associated Fatty Acid-Binding Protein ELISA kitFabppm ELISA kitTransaminase A ELISA kitGot2 ELISA kitGot-2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
