| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Indoleamine 2 3-dioxygenase 2 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:2, 500-1:5, 000 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Tissue Specificity | Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon. Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%). |
| Function | Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance. |
| Peptide Name | Indoleamine 2 -3-Dioxygenase 2Ido-2Indoleamine 2 -3-Dioxygenase-Like Protein 1Indoleamine-Pyrrole 2 -3-Dioxygenase-Like Protein 1 |
| Database Links | Reactome: R-HSA-71240 |
| Alternative Peptide Names | Indoleamine 2 -3-Dioxygenase 2 proteinIdo-2 proteinIndoleamine 2 -3-Dioxygenase-Like Protein 1 proteinIndoleamine-Pyrrole 2 -3-Dioxygenase-Like Protein 1 proteinIDO2 proteinINDOL1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
