• Human VTCN1 (V-Set Domain Containing T-Cell Activation Inhibitor 1) Sandwich ELISA Kit Ready-To-Use (STJE0019458)

Human VTCN1 (V-Set Domain Containing T-Cell Activation Inhibitor 1) Sandwich ELISA Kit Ready-To-Use (STJE0019458)

SKU:
STJE0019458

£481.50 - £659.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.054ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This VTCN1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: VTCN1
Gene ID: 79679
Uniprot ID: VTCN1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.
Post Translational Modifications N-glycosylated.
Function Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Protein Name V-Set Domain-Containing T-Cell Activation Inhibitor 1
B7 Homolog 4
B7-H4
B7h.5
Immune Costimulatory Protein B7-H4
Protein B7s1
T-Cell Costimulatory Molecule B7x
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Expressed At The Cell Surface
A Soluble Form Has Also Been Detected
Alternative ELISA Names V-Set Domain-Containing T-Cell Activation Inhibitor 1 ELISA kit
B7 Homolog 4 ELISA kit
B7-H4 ELISA kit
B7h.5 ELISA kit
Immune Costimulatory Protein B7-H4 ELISA kit
Protein B7s1 ELISA kit
T-Cell Costimulatory Molecule B7x ELISA kit
VTCN1 ELISA kit
B7H4 ELISA kit
UNQ659 ELISA kit
PRO1291 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance