| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human VEGF-B-N-Fc protein was developed from hek293 cells and has a target region of N-Fc. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VEGFB |
| Gene ID: |
7423 |
| Uniprot ID: |
VEGFB_HUMAN |
| Immunogen Region: |
Pro22-Ala207 |
| Immunogen: |
Recombinant Human VEGF-B Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Pro22-Ala207) of human VEGFB (Accession #P49765) fused with an Fc tag at the N-terminus. |
| Post Translational Modifications | VEGF-B186 is O-glycosylated. |
| Function | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
| Protein Name | Vascular Endothelial Growth Factor BVegf-BVegf-Related FactorVrf |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-194313Reactome: R-HSA-195399 |
| Cellular Localisation | SecretedSecreted But Remains Associated To Cells Or To The Extracellular Matrix Unless Released By Heparin |
| Alternative Protein Names | Vascular Endothelial Growth Factor B proteinVegf-B proteinVegf-Related Factor proteinVrf proteinVEGFB proteinVRF protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
