• Human TRPM7 (Transient Receptor Potential Cation Channel Subfamily M, Member 7) Sandwich ELISA Kit (STJE0012822)

Human TRPM7 (Transient Receptor Potential Cation Channel Subfamily M, Member 7) Sandwich ELISA Kit (STJE0012822)

SKU:
STJE0012822

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 33pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This TRPM7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: TRPM7
Gene ID: 54822
Uniprot ID: TRPM7_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Autophosphorylated.
Function Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).
Protein Name Transient Receptor Potential Cation Channel Subfamily M Member 7
Channel-Kinase 1
Long Transient Receptor Potential Channel 7
Ltrpc-7
Ltrpc7
Database Links Reactome: R-HSA-3295583
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Transient Receptor Potential Cation Channel Subfamily M Member 7 ELISA kit
Channel-Kinase 1 ELISA kit
Long Transient Receptor Potential Channel 7 ELISA kit
Ltrpc-7 ELISA kit
Ltrpc7 ELISA kit
TRPM7 ELISA kit
CHAK1 ELISA kit
LTRPC7 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance