Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
33pg/mL |
Detection Limit: |
78.1-5000pg/mL |
Short Description: |
This TRPM7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
TRPM7 |
Gene ID: |
54822 |
Uniprot ID: |
TRPM7_HUMAN |
Sample Type: |
tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Autophosphorylated. |
Function | Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). |
Protein Name | Transient Receptor Potential Cation Channel Subfamily M Member 7Channel-Kinase 1Long Transient Receptor Potential Channel 7Ltrpc-7Ltrpc7 |
Database Links | Reactome: R-HSA-3295583 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Transient Receptor Potential Cation Channel Subfamily M Member 7 ELISA kitChannel-Kinase 1 ELISA kitLong Transient Receptor Potential Channel 7 ELISA kitLtrpc-7 ELISA kitLtrpc7 ELISA kitTRPM7 ELISA kitCHAK1 ELISA kitLTRPC7 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance