• Human TPM2 (Tropomyosin 2 Beta) Sandwich ELISA Kit Ready-To-Use (STJE0019148)

Human TPM2 (Tropomyosin 2 Beta) Sandwich ELISA Kit Ready-To-Use (STJE0019148)

SKU:
STJE0019148

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.247ng/mL
Detection Limit: 0.625-40ng/mL
Short Description: This TPM2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: TPM2
Gene ID: 7169
Uniprot ID: TPM2_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Present in primary breast cancer tissue, absent from normal breast tissue.
Post Translational Modifications Phosphorylated on Ser-61 by PIK3CG. Phosphorylation on Ser-61 is required for ADRB2 internalization.
Function Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization.
Protein Name Tropomyosin Beta Chain
Beta-Tropomyosin
Tropomyosin-2
Database Links Reactome: R-HSA-390522
Reactome: R-HSA-445355
Cellular Localisation Cytoplasm
Cytoskeleton
Associates With F-Actin Stress Fibers
Alternative ELISA Names Tropomyosin Beta Chain ELISA kit
Beta-Tropomyosin ELISA kit
Tropomyosin-2 ELISA kit
TPM2 ELISA kit
TMSB ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance