Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human TNFRSF18/CD357-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Gene Symbol: |
TNFRSF18 |
Gene ID: |
8784 |
Uniprot ID: |
TNR18_HUMAN |
Immunogen: |
Recombinant Human CD3 Delta Protein is produced by mammalian expression system. The target protein is expressed with sequence (Met1-Glu161) of human GITR (Accession #Q9Y5U5) fused with a 6xHis tag at the C-terminus. |
Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 18Activation-Inducible Tnfr Family ReceptorGlucocorticoid-Induced Tnfr-Related ProteinCd Antigen Cd357 |
Database Links | Reactome: R-HSA-5669034Reactome: R-HSA-8877330 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 18 proteinActivation-Inducible Tnfr Family Receptor proteinGlucocorticoid-Induced Tnfr-Related Protein proteinCd Antigen Cd357 proteinTNFRSF18 proteinAITR proteinGITR proteinUNQ319 proteinPRO364 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance