| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human TMIGD2/CD28H/IGPR1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | TMIGD2 |
| Gene ID: | 126259 |
| Uniprot ID: | TMIG2_HUMAN |
| Immunogen Region: | Leu23-Gly150 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | N-glycosylated. |
| Function | Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
| Protein Name | Transmembrane And Immunoglobulin Domain-Containing Protein 2Cd28 HomologImmunoglobulin And Proline-Rich Receptor 1Igpr-1 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Transmembrane And Immunoglobulin Domain-Containing Protein 2 proteinCd28 Homolog proteinImmunoglobulin And Proline-Rich Receptor 1 proteinIgpr-1 proteinTMIGD2 proteinCD28H proteinIGPR1 proteinUNQ3059 proteinPRO9879 protein |
Information sourced from Uniprot.org