| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.062ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This TKTL1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
TKTL1 |
| Gene ID: |
8277 |
| Uniprot ID: |
TKTL1_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Widely expressed. Expressed in endothelial cells and in peripheral neurons (at protein level). Isoform 3: Not expressed in fetal neocortex. Isoform 4: Expressed in fetal neocortex. |
| Post Translational Modifications | |
| Function | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Isoform 4: During fetal neocortex development, may be essential to maintain the full number of basal radial glia (bRG). bRG are neural progenitor cells that undergo asymmetric divisions, generating a bRG (self-renewal) and a neuron, in contrast to basal intermediate progenitors (bIPs), which typically divide once to give rise to 2 neurons. bRG generate more cortical neurons over time than bIPs. |
| Protein Name | Transketolase-Like Protein 1Transketolase 2Tk 2Transketolase-Related Protein |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Transketolase-Like Protein 1 ELISA kitTransketolase 2 ELISA kitTk 2 ELISA kitTransketolase-Related Protein ELISA kitTKTL1 ELISA kitTKR ELISA kitTKT2 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
