| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
8.3pg/mL |
| Detection Limit: |
15.6-1000pg/mL |
| Short Description: |
This TCIRG1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Tissue Specificity | Isoform long is highly expressed in osteoclastomas. Isoform short is highly expressed in thymus. |
| Post Translational Modifications | |
| Function | Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Seems to be directly involved in T-cell activation. |
| Protein Name | V-Type Proton Atpase 116 Kda Subunit A 3V-Atpase 116 Kda Subunit A 3Osteoclastic Proton Pump 116 Kda SubunitOc-116 KdaOc116T-Cell Immune Regulator 1T-Cell Immune Response Cdna7 ProteinTirc7Vacuolar Proton Translocating Atpase 116 Kda Subunit A Isoform 3 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-6798695Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | V-Type Proton Atpase 116 Kda Subunit A 3 ELISA kitV-Atpase 116 Kda Subunit A 3 ELISA kitOsteoclastic Proton Pump 116 Kda Subunit ELISA kitOc-116 Kda ELISA kitOc116 ELISA kitT-Cell Immune Regulator 1 ELISA kitT-Cell Immune Response Cdna7 Protein ELISA kitTirc7 ELISA kitVacuolar Proton Translocating Atpase 116 Kda Subunit A Isoform 3 ELISA kitTCIRG1 ELISA kitATP6N1C ELISA kitATP6V0A3 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
