Human SRSF7 protein (Recombinant) (N-His) (STJP010179)

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STJP010179
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SRSF7-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SRSF7
Gene ID: 6432
Uniprot ID: SRSF7_HUMAN
Immunogen Region: Met1-Ser128
Immunogen: Homo sapiens (Human)
Post Translational Modifications Extensively phosphorylated on serine residues in the RS domain.
Function Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway).enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
Protein Name Serine/Arginine-Rich Splicing Factor 7
Splicing Factor 9g8
Splicing Factor - Arginine/Serine-Rich 7
Database Links Reactome: R-HSA-159236
Reactome: R-HSA-72163
Reactome: R-HSA-72165
Reactome: R-HSA-72187
Reactome: R-HSA-72203
Reactome: R-HSA-73856
Cellular Localisation Nucleus
Cytoplasm
Alternative Protein Names Serine/Arginine-Rich Splicing Factor 7 protein
Splicing Factor 9g8 protein
Splicing Factor - Arginine/Serine-Rich 7 protein
SRSF7 protein
SFRS7 protein

Information sourced from Uniprot.org