Host: |
E. coli |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : |
Recombinant-Human SRSF7-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
Formulation: |
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: |
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: |
SRSF7 |
Gene ID: |
6432 |
Uniprot ID: |
SRSF7_HUMAN |
Immunogen Region: |
Met1-Ser128 |
Immunogen: |
Homo sapiens (Human) |
Post Translational Modifications | Extensively phosphorylated on serine residues in the RS domain. |
Function | Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway).enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific. |
Protein Name | Serine/Arginine-Rich Splicing Factor 7Splicing Factor 9g8Splicing Factor - Arginine/Serine-Rich 7 |
Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
Cellular Localisation | NucleusCytoplasm |
Alternative Protein Names | Serine/Arginine-Rich Splicing Factor 7 proteinSplicing Factor 9g8 proteinSplicing Factor - Arginine/Serine-Rich 7 proteinSRSF7 proteinSFRS7 protein |
Information sourced from Uniprot.org