Human SLC17A5 protein (Recombinant) (N-GST & C-His) (STJP009724)

SKU:
STJP009724
$443.48 - $1,940.63
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLC17A5-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLC17A5
Gene ID: 26503
Uniprot ID: S17A5_HUMAN
Immunogen Region: Val65-Gln108
Immunogen: Homo sapiens (Human)
Function Multifunctional anion transporter that operates via two distinct transport mechanisms, namely proton-coupled anion cotransport and membrane potential-dependent anion transport. Electroneutral proton-coupled acidic monosaccharide symporter, with a sugar to proton stoichiometry of 1:1. Exports glucuronic acid and free sialic acid derived from sialoglycoconjugate degradation out of lysosomes, driven by outwardly directed lysosomal pH gradient. May regulate lysosome function and metabolism of sialylated conjugates that impact oligodendrocyte lineage differentiation and myelinogenesis in the central nervous system. Electrogenic proton-coupled nitrate symporter that transports nitrate ions across the basolateral membrane of salivary gland acinar cells, with nitrate to proton stoichiometry of 2:1. May contribute to nitrate clearance from serum by salivary glands, where it is further concentrated and secreted in the saliva. Uses membrane potential to drive the uptake of acidic amino acids and peptides into synaptic vesicles. Responsible for synaptic vesicular storage of L-aspartate and L-glutamate in pinealocytes as well as vesicular uptake of N-acetyl-L-aspartyl-L-glutamate neuropeptide, relevant to aspartegic-associated glutamatergic neurotransmission and activation of metabotropic receptors that inhibit subsequent transmitter release. Receptor for CM101, a polysaccharide produced by group B Streptococcus with antipathoangiogenic properties.
Protein Name Sialin
H(+/Nitrate Cotransporter
H(+/Sialic Acid Cotransporter
Ast
Membrane Glycoprotein Hp59
Solute Carrier Family 17 Member 5
Vesicular Excitatory Amino Acid Transporter
Veat
Database Links Reactome: R-HSA-4085001
Reactome: R-HSA-428643
Reactome: R-HSA-5619035
Cellular Localisation Basolateral Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Lysosome Membrane
Alternative Protein Names Sialin protein
H(+/Nitrate Cotransporter protein
H(+/Sialic Acid Cotransporter protein
Ast protein
Membrane Glycoprotein Hp59 protein
Solute Carrier Family 17 Member 5 protein
Vesicular Excitatory Amino Acid Transporter protein
Veat protein
SLC17A5 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP011289 Human SOX9, N-GST & C-His protein (Recombinant) (N-GST & C-His) (STJP011289) E. coli
STJP006349 Human SLC17A5 protein (Recombinant) (N-His) (STJP006349) E. coli
STJP009619 Human WAS protein (Recombinant) (N-GST & C-His) (STJP009619) E. coli
STJP007410 Human MYL3 protein (Recombinant) (N-GST & C-His) (STJP007410) E. coli
STJP007465 Human FXYD1 protein (Recombinant) (N-GST & C-His) (STJP007465) E. coli

Related Products

!