| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.065ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This SF3B3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
SF3B3 |
| Gene ID: |
23450 |
| Uniprot ID: |
SF3B3_HUMAN |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | Splicing Factor 3b Subunit 3Pre-Mrna-Splicing Factor Sf3b 130 Kda SubunitSf3b130Staf130Spliceosome-Associated Protein 130Sap 130 |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Splicing Factor 3b Subunit 3 ELISA kitPre-Mrna-Splicing Factor Sf3b 130 Kda Subunit ELISA kitSf3b130 ELISA kitStaf130 ELISA kitSpliceosome-Associated Protein 130 ELISA kitSap 130 ELISA kitSF3B3 ELISA kitKIAA0017 ELISA kitSAP130 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
