Applications: |
ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.056ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This SESN3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
SESN3 |
Gene ID: |
143686 |
Uniprot ID: |
SESN3_HUMAN |
Sample Type: |
tissue homogenates or other biological fluids. |
Tissue Specificity | Widely expressed. |
Post Translational Modifications | |
Function | May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein. |
Protein Name | Sestrin-3 |
Database Links | Reactome: R-HSA-5628897 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Sestrin-3 ELISA kitSESN3 ELISA kitSEST3 ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance